E101: Antipsychotics: D2 and 5HT2A Receptor Activity

Today I will discuss how antipsychotics exert their positive effects on D2 and 5HT2A receptors. I will talk about intrinsic activity, partial agonism, pre-synaptic activity, antagonism, and the variety of effects the different antipsychotics exert on these receptors that changes how they work. This is a fundamental episode for understanding the differences and the mechanism of action of the antipsychotics so don't miss it!