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This Week in Microbiology

343: Nucleotides to the Defense

44 min25 oktober 2025

TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides.

Hosts: Michael Schmidt and Mark O. Martin

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Links for this episode:

  • Decoy cyclic nucleotides in phage defense (Nature)

  • CRISPR defense with nucleotides (Nature)

  • A decoy defence molecule to set a trap for viruses (Nature)

  • Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol)

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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