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TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease

1 tim 10 min•24 maj 2022

TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson's disease.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Links for this episode

Gut-brain alpha-synuclein transport in PD (Neuron)
Gut has a mind of its own (Colbert Report)
Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

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