TWiP 205: Two for the price of one

The TWiP team solves the case of the Pregnant Ghanian Living Near a River, and reveal emodepside, a drug for treatment of onchocerciasis.

Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula

Download TWiP #205 (56 MB .mp3, 93 minutes)

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• Emodepside for onchocerciasis (PlOS NTD)
• Hero: Dr. Mwelecele Ntuli Malecela
• Letters read on TWiP 205

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Case Study for TWiP 205

Two women, 80s and 50s. Former had 9 children, lives in Ghanian village with large lagoon, many mosquitoes. Concerned about chronic swelling of left leg, groin area for much of her life. Walks barefoot. 50 yo with 4 children, both legs started to swell, cold, mosquito bites. With time left leg becomes hard, swollen, disfigured. Has gone to hospital for ulceration. Common problem in her village, mostly women but some men. Problems getting access to medications. 

Send your case diagnosis, questions and comments to [email protected]

Music by Ronald Jenkees