Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity’s “buy, fix, and flip” strategy? Don’t miss this deep dive into the latest tech and startup news!
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Timestamps:
(0:00) Jason and Alex kick off the show. (1:58) DeepSeek's market impact and Project Stargate (4:18) Innovation, H100 GPUs, and open-source AI models (8:41) Jevons paradox, Pat Gelsinger's analogy, and AI efficiency
(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (13:25) AI's benefits for startups and privacy concerns (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (19:51) AI optimization vs. hardware consumption
(22:20) OpenAI's revenue, valuation, and NVIDIA's market value (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist (33:21) Unified AI digital assistants and DeepSeq's new model (35:01) AI's role in venture capital and team size reduction (41:04) China's influence and DeepSeek's market impact (43:22) Startup shutdowns and potential for increased M&A activity (53:02) Nvidia's historical analysis, risks of leverage, and SailPoint's IPO
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LinkedIn: https://www.linkedin.com/in/alexwilhelm
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LinkedIn: https://www.linkedin.com/in/jasoncalacanis
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Thank you to our partners:
(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist *
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
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Substack: https://twistartups.substack.com
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