This Week in Startups

Thinking Machines’ RECORD seed round, VC Geoff Lewis, and MORE | E2152

68 min • 17 juli 2025

Today’s show:

Jason and Alex tackle a full tech and business news docket on today’s show, including Jason’s big SF trip with Launch Accelerator’s 34th cohort, some peculiar social media posts from VC Geoff Lewis, a look inside the HUGE seed rounds being commanded by early-stage AI startups, crunching the numbers on how much compute data centers need to sell before they’re profitable, Polymarket asks who will be the next CEO of X and MUCH MUCH MORE.

Join us for the longest-running and most in-depth podcast on Earth for startup founders.


Timestamps:

(00:00) INTRO

(01:31) Jason’s in SF with LAUNCH Accelerator cohort 34… His take on the mood in Silicon Valley.

(07:52) Odd X posts from Bedrock Capital’s Geoff Lewis… what does it all mean?

(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist

(14:44) Ask JCal: What founders can do to guard their own mental health and well-being

(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!

(22:04) Thinking Machines Lab set a new record for a seed round: what’s going on with these MEGA deals?

(28:51) Alex (and Kabir from LAUNCH’s research team) investigated the economics of data centers… just HOW MUCH can you make from selling compute? And how long does it TAKE to turn a profit?

(30:52) Bolt - Don’t be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.

(37:09) Superintelligence vs. AGI: Jason thinks we’re still more than 2-3 years away…

(39:52) GPx is not a traditional VC fund: here’s what industry vet Brian Singerman is up to

(49:37) The importance of setting your own corporate culture… before it gets set for you!

(58:15) Polymarket has ideas for the next X CEO… see where Jason ranks on the list!

(01:03:18) Reddit wants to know… Do investors judge founders negatively who rely on lots of AI tools?


Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp


Follow Lon:

X: https://x.com/lons


Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm


Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis


Thank you to our partners:

(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist

(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!

(30:52) Bolt - Don’t be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.


Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland


Check out Jason’s suite of newsletters: https://substack.com/@calacanis


Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com


Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Senaste avsnitt

Podcastbild

00:00 -00:00
00:00 -00:00