Brian Armstrong is the co-founder and CEO of Coinbase, a leading cryptocurrency company that provides exchange, brokerage, and custody services to 100M+ verified users in over 100 countries. Founded in 2012, Coinbase went public in 2021 on the NASDAQ under the ticker COIN and as of August 2025 has a market cap of $83 billion. Brian is also the co-founder of New Limit, a longevity biotech company on a mission to significantly extend human lifespan that recently raised a $130M Series B led by Kleiner Perkins and angels including John and Patrick Collison, Elad Gil, and Joshua Kushner, among others.
We covered:
- Working with the government
- When to jump to the hot new thing
- Choosing what frontiers to prioritize
- The inner game of being contrarian
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Timestamps:
(0:00) Intro
(0:26) Becoming the everything chain
(4:20) Story behind the GENIUS Act
(5:33) Working with regulators
(10:45) The future of crypto and the government
(17:10) When to jump to the hot new thing
(23:03) Choosing what frontiers to prioritize
(29:59) Brain-computer interface tech
(34:48) Inside the mind of a contrarian
(43:52) Creating a sustainable lifestyle
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More on Brian:
https://www.coinbase.com/
https://www.newlimit.com/
https://x.com/brian_armstrong
More on Jack:
https://www.altcap.com/
https://x.com/jaltma
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