Fighting Resistant Hookworms: Inside the AAVP Task Force's New Diagnosis and Treatment Guidelines

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Hookworm cases that “just won’t clear” are no longer a weird outlier, and that should change how we practice. We sit down with parasitology expert Dr. Ray Kaplan to unpack the American Association of Veterinary Parasitologists (AAVP) Hookworm Task Force recommendations on diagnosing and treating multidrug-resistant canine hookworms, including what clinics can do right now to stop guessing and start confirming.

We talk through how this problem came to light, why drug-resistant hookworms likely gained traction in greyhound breeding and racing environments, and why it’s now a pet dog problem across breeds and regions. We also zoom out to the biology that makes Ancylostoma caninum such a persistent threat, from multiple routes of infection to the possibility of “larva leak,” and then get practical about what should raise suspicion. 

From there, we map out a clear diagnostic path. We discuss the value of a two-week post-treatment fecal recheck, how to use a fecal egg count reduction test to quantify efficacy, and what “good” reduction should look like. We cover the task force approach to treatment and testing across the three drug classes (topical moxidectin, pyrantel, and benzimidazoles like fenbendazole or febantel), the limits of current PCR testing, and when extra-label emodepside enters the conversation with important safety precautions. If you want a grounded, clinic-ready framework that also addresses environmental contamination and zoonotic risk, this one’s for you. 

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JAVMA article: https://doi.org/10.2460/javma.26.02.0094

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