This newsletter discusses the multifaceted challenges organizations face when adopting generative AI, focusing on a phased approach. It emphasizes the importance of a structured, prioritized roadmap addressing ethical considerations, data quality, and organizational readiness alongside technological aspects. The author presents a three-wave model for adoption—personal productivity, team collaboration, and enterprise transformation—advising iterative progress and stakeholder alignment. The newsletter draws on real-world experiences from the author's work with clients at AWS, particularly within the healthcare and life sciences sectors, offering practical advice and insights to accelerate successful generative AI implementation.