078-Identifying gut microbial bile acid metabolic enzymes

This article details the identification of gut microbial bile acid metabolic enzymes through an AI-assisted pipeline called BEAUT. The research, conducted by Ding et al., uncovers novel enzymes like MABH, responsible for hydrolyzing specific bile acids, and ADS, which creates an unreported skeleton bile acid, 3-acetoDCA. The paper explores the structural basis and catalytic mechanisms of these enz...去小宇宙查看完整单集简介
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