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Paper Talk

095-OpenCell: Mapping Human Cell Organization

22 min28 september 2025
This research introduces OpenCell, a comprehensive resource developed through high-throughput CRISPR-mediated genome editing to map the architecture of the human proteome. The project generated 1310 fluorescently tagged human cell lines, enabling live-cell imaging of protein localization and immunoprecipitation-mass spectrometry (IP-MS) to characterize protein interactions. By combining these adva...去小宇宙查看完整单集简介
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