097-Immature Neutrophils in Bone Metastases

This paper investigates the role of immature neutrophils in bone metastases, a form of cancer that is notoriously resistant to immune checkpoint blockade (ICB) therapy. The research highlights that the protein DKK1 is instrumental in promoting an immature and immunosuppressive state in neutrophils. Furthermore, the study identifies the DKK1-CKAP4-CHI3L3 signaling pathway as a key mechanism through...去小宇宙查看完整单集简介
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