1002-Targeting RAS-GTP Active State in KRAS Mutant Cancer

This research highlights the therapeutic potential of RAS(ON) multi-selective inhibitors for treating cholangiocarcinoma (CCA), a lethal bile duct cancer often driven by KRAS mutations. Using various preclinical models and patient data, the authors demonstrate that these inhibitors effectively block the active state of RAS proteins to trigger tumor regression and improved survival. The findings id...去小宇宙查看完整单集简介
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