1006-When Tissue Tension Creates a Mutagenic Niche

Research highlights a groundbreaking discovery that physical tissue stiffness acts as a direct catalyst for genetic mutations in cancer. This process begins when a rigid extracellular environment triggers a cellular chain reaction, signaling epithelial cells to recruit inflammatory macrophages. These immune cells respond to the mechanical pressure by releasing genotoxic aldehydes and reactive oxyg...去小宇宙查看完整单集简介
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