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Paper Talk

1033-CSC-Driven Immune Evasion via Vesicle Signaling

24 min26 maj 2026
This research identifies how cancer stem cells (CSCs) in triple-negative breast cancer orchestrate immune evasion through the secretion of extracellular vesicles (EVs). These vesicles carry the protein TSPAN8, which acts as a ligand that binds to CD103 receptors on T cells to trigger a specific metabolic signaling axis. This process drives the differentiation and expansion of immunosuppressive reg...去小宇宙查看完整单集简介
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