113-A view on drug resistance in cancer

This article addresses the multifaceted problem of drug resistance in cancer therapy. The authors articulate a framework for understanding resistance by defining its key biological determinants, including tumor burden and growth kinetics, heterogeneity, physical barriers, the immune system, and undruggable genomic drivers. They propose four general solutions to overcome resistance: earlier detecti...去小宇宙查看完整单集简介
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