129-Tryptophan Metabolism Restricts TLS Maturation

This article presents a study utilizing spatial transcriptomics (Stereo-seq) to investigate the heterogeneity and developmental states of tertiary lymphoid structures (TLSs) in hepatocellular carcinoma (HCC) patients. The core finding is that tumor-derived tryptophan metabolism restricts the maturation of TLSs, classifying traditionally "immature" TLSs into distinct conforming and deviating types ...去小宇宙查看完整单集简介
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