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133-Highly Multiplexed 3D Tumor Profiling

30 min12 oktober 2025
This article introduces a novel technique called three-dimensional cyclic immunofluorescence (3D CyCIF) for high-plex, high-resolution imaging of cell states and immune niches within human tumor tissues. The authors demonstrate that traditional thin tissue sections, typically 5 µm thick, result in fragmented cells and inaccurate phenotyping, whereas sections eightfold to tenfold thicker (30–40 µm)...去小宇宙查看完整单集简介
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