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Paper Talk

136-ETC Suppression Boosts Resilience to Excitotoxicity

19 min14 oktober 2025
This article focuses on how mitochondrial activity influences the resilience of nociceptors, or pain-sensing neurons, against excitotoxicity, which is cell death caused by overexcitation and calcium overload. Through a genome-wide screen, the authors identified that the electron transport chain (ETC) is a key determinant of cellular protection. Lowering ETC expression or activity enhances resilien...去小宇宙查看完整单集简介
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