139-T Cell Exhaustion Driven by Proteostasis Stress

This paper reports on the discovery of a distinct mechanism driving T cell exhaustion (Tex cells) in the context of chronic infections and cancer. The authors utilized proteomic analysis to identify a unique cellular stress response, termed Tex-PSR (proteotoxic stress response), which is characterized by an unusual increase in global protein synthesis and the accumulation of protein aggregates, de...去小宇宙查看完整单集简介
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