158-Single-Cell Landscape of Pan-Cancer Brain Metastases

The article details the creation of a comprehensive pan-cancer human brain metastases (BrM) atlas using single-cell resolution transcriptomics, integrating data from 108 BrM samples and 111 primary tumor (PT) samples. Key findings include the identification of increased chromosomal instability (CIN) and a conserved neural-like metaprogram in malignant tumor cells (MTCs) across different cancer typ...去小宇宙查看完整单集简介
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