161-sRCC Immunobiology and Immunotherapy Prediction

This paper investigates why sarcomatoid renal cell carcinoma (sRCC) is highly aggressive yet responds well to immune checkpoint blockade (ICB) therapy, a paradoxical clinical observation. Through single-cell and bulk transcriptomic analyses of over 3,000 tumors, the authors detail a robust anti-tumor immune microenvironment in sRCC characterized by activated and exhausted T cells, prevalent tertia...去小宇宙查看完整单集简介
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