169-An OTX2-PAX3 signaling axis in Group 3 Medulloblastoma

This article investigates the molecular mechanisms driving Group 3 medulloblastoma (MB), the most aggressive subtype of this common pediatric brain tumor. The research centers on the OTX2 oncogene, demonstrating that it promotes tumor growth by repressing neural differentiation through a newly identified OTX2-PAX3 signaling axis. Using multiomic analyses, the study finds that OTX2 silencing derepr...去小宇宙查看完整单集简介
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