190-Spatial Proteomics Reveals Primary Cilia Heterogeneity

This article utilizes antibody-based spatial proteomics and 3D confocal imaging to map the locations of 715 proteins within human primary cilia across three different cell lines, creating a spatial cilia atlas. Key findings highlight the extensive heterogeneity of the ciliary proteome, noting that 69% of identified proteins are cell-type specific and 78% show variation across individual cilia, sug...去小宇宙查看完整单集简介
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