196-TET2-Mutant Hematopoiesis Enhances ICT Response

This article details research on how TET2-mutant clonal hematopoiesis (CH) affects the response to immune checkpoint therapy (ICT) in solid tumors. The authors demonstrate that the presence of the TET2 mutation in myeloid cells, specifically macrophages, enhances their ability to function as antigen-presenting cells, particularly in response to IFNγ signaling. Through mouse models and analysis of ...去小宇宙查看完整单集简介
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