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Paper Talk

208-PHLOWER: Inferring Differentiation Trajectories

17 min4 november 2025
The article introduces PHLOWER, a novel computational method for inferring complex, multi-branching cell differentiation trajectories from single-cell multimodal data, such as RNA sequencing and ATAC sequencing. By leveraging the harmonic component of the Hodge decomposition on simplicial complexes, PHLOWER translates cell differentiation into flow embeddings that facilitate the reconstruction of ...去小宇宙查看完整单集简介
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