221-RNA-Stabilized Coat Proteins for Single mRNA Imaging

The paper introduce novel RNA-stabilized coat proteins, named dMCP and dPCP, engineered to overcome the challenge of high background noise in live-cell RNA imaging. These variants of the traditional MS2 and PP7 coat proteins are designed to rapidly degrade in the absence of their target RNA ligands, ensuring that only the RNA-bound proteins produce a fluorescent signal. Through techniques like cir...去小宇宙查看完整单集简介
前往小宇宙评论区与主播互动