The article details the development and application of precisION, an interactive, open-source software package for analyzing data from native top-down mass spectrometry (nTDMS). This new computational framework uses a data-driven fragment-level open search to overcome the limitations of current nTDMS methods, which often fail to detect uncharacterized or low-abundance protein modifications (PTMs) ...去小宇宙查看完整单集简介
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