231-Rapid Epigenomic Classification of Acute Leukemia

The article describes the development and validation of a new framework, utilizing genome-wide DNA methylation profiling and a neural network called MARLIN, for the rapid and precise classification of acute leukemia. Researchers first created a comprehensive reference cohort of over 2,500 samples to define 38 distinct methylation classes across various acute leukemia lineages, demonstrating that t...去小宇宙查看完整单集简介
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