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234-Spatial Niches in Diffuse Large B Cell Lymphoma

20 min•16 november 2025
The article details a multi-modal spatial characterization of tumor immune microenvironments in diffuse large B-cell lymphoma (DLBCL). Researchers used highly multiplexed spatial transcriptomics (CosMx) and proteomics (CODEX) on 78 DLBCL tumors to define seven distinct cellular niches characterized by unique cell compositions and communication patterns. The study reveals that the functional states...去小宇宙查看完整单集简介
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