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Paper Talk

247-Remodeling Cold Tumors for Immunotherapy

20 min20 november 2025
This review addresses the major challenge in cancer immunotherapy posed by "cold" tumors, which resist treatment due to low immune cell infiltration and an immunosuppressive tumor microenvironment (TME). The authors meticulously examine the molecular and cellular mechanisms of this resistance, categorizing them into three "Cs": camouflage (impeding immune priming and infiltration), coercion (suppr...去小宇宙查看完整单集简介
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