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248-Reprogramming neuroblastoma by Diet Polyamine Depletion

20 min20 november 2025
The paper details research on treating highly lethal childhood cancer neuroblastoma. The study investigates combining the existing drug difluoromethylornithine (DFMO), which inhibits polyamine synthesis, with a proline- and arginine-free diet to enhance therapeutic outcomes. Researchers found that this combined approach drastically depleted the polyamine precursor ornithine, leading to a significa...去小宇宙查看完整单集简介
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