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Paper Talk

251-CellNEST: Cell-Cell Networks in Spatial Transcriptomics

17 min21 november 2025
The paper introduces CellNEST, a novel computational model utilizing Graph Attention Networks (GAT) and Deep Graph Infomax (DGI) to overcome challenges in detecting cell-cell communication (CCC) from spatial transcriptomics data, which is essential for understanding diseases like cancer. Existing methods often suffer from high false-positive rates and only detect single ligand-receptor pairs, whil...去小宇宙查看完整单集简介
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