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Paper Talk

252-Multiscale Integrated Cell Map of Protein Assemblies

25 min21 november 2025
The paper outlines the creation of a global, multiscale map of human subcellular architecture in U2OS osteosarcoma cells, integrating two complementary data sources: biophysical protein interactions determined by affinity purification–mass spectrometry (AP–MS) and protein localization images from immunofluorescence (IF). The researchers employed a self-supervised machine learning model to fuse the...去小宇宙查看完整单集简介
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