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253-Rewiring of cortical glucose metabolism fuels GBM growth

12 min22 november 2025
The paper details a study investigating the distinct ways glioblastoma (GBM) tumors metabolize glucose compared to healthy brain tissue. Using stable isotope tracing in human patients and mice, the researchers determined that while the cortex uses glucose primarily for physiological functions like the TCA cycle and neurotransmitter synthesis, aggressive GBM redirects glucose-derived carbons to pro...去小宇宙查看完整单集简介
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