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Paper Talk

274-AGE-Induced Viscoelasticity Drives HCC via TNS1

15 min28 november 2025
The aper presents research demonstrating that changes in the extracellular matrix (ECM) viscoelasticity, specifically caused by Advanced Glycation End-products (AGEs), promote the progression of liver cancer (hepatocellular carcinoma or HCC) in pre-cirrhotic conditions, independent of matrix stiffness. The accumulation of AGEs, a characteristic of Type 2 diabetes mellitus (T2DM) and non-alcoholic ...去小宇宙查看完整单集简介
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