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Paper Talk

290-Perturb-Seq: Single-Cell Profiling of Genetic Screens

21 min3 december 2025
The paper introduces and explains Perturb-seq, a new experimental and computational technology that combines pooled CRISPR-based genetic screening with single-cell RNA sequencing (scRNA-seq) to analyze complex biological circuits. This method allows researchers to study the transcriptional effects and genetic interactions of numerous perturbations simultaneously within individual cells. The accomp...去小宇宙查看完整单集简介
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