307-Spatial fibroblast niches define Crohn’s fistulae

This paper details a comprehensive molecular analysis of intestinal fistulae, the penetrating lesions characteristic of Crohn’s disease, using advanced single-cell RNA sequencing and spatial transcriptomics (ST) on tissue samples from 92 individuals. The research defined a unique and abundant cell type called Fistula-Associated Fibroblasts (FAS cells), which are central to the persistence of the d...去小宇宙查看完整单集简介
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