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Paper Talk

319-Spacedust: Discovery of Conserved Gene Clusters

18 min16 december 2025
The paper introduces Spacedust, a novel computational tool created for the systematic, de novo discovery of conserved gene clusters (CGCs) in microbial and viral genomes, aiming to overcome the bottleneck of poor functional annotation in metagenomics. The software improves upon prior methods by employing highly sensitive protein structure comparison via Foldseek to find remote homologous matches t...去小宇宙查看完整单集简介
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