325-Structural Basis of Toxin Targeting by UmbA Lectins

The article examines the intricate mechanism used by umbrella toxins—complex antibacterial particles secreted by Streptomyces—for competition. This mechanism relies on UmbA lectin domains mediating species-specific binding to a novel cell surface carbohydrate receptor: the teichuronic acid-wall teichoic acid (TUA-WTA) hybrid. Resistance studies and cryo-electron microscopy (cryo-EM) confirmed that...去小宇宙查看完整单集简介
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