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Paper Talk

326-mTOR Regulation of Cytoskeleton Drives Mitoxyperilysis

14 min19 december 2025
This article by Wang et al. introduces a novel lytic cell death pathway, termed mitoxyperilysis. This process is triggered by the simultaneous occurrence of innate immune activation and metabolic disruption (IIAMD), which together cause mitochondrial oxidative stress and damage. The core mechanistic step, which the authors name mitoxyperiosis, involves damaged mitochondria maintaining prolonged ph...去小宇宙查看完整单集简介
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