337-Rod-shaped microglia in Neurodegeneration

This article investigates the relationship between neuronal hyperactivity and specialized rod-shaped microglia in a mouse model of TDP-43-related neurodegeneration, a condition relevant to Amyotrophic Lateral Sclerosis (ALS). The authors use advanced techniques, including spatial and single-cell RNA sequencing and in vivo calcium imaging, to demonstrate that early cortical hyperactivity induces th...去小宇宙查看完整单集简介
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