338-NFATc1 Constrains Bystander Activation of CD8+ T Cells

This article examines the molecular regulation of bystander activation in human memory CD8+ T cells that is induced by Interleukin-15 (IL-15). The authors, Lee et al., found that while IL-15 causes these T cells to exhibit NK-like cytotoxicity and elevated expression of markers like NKG2D, concurrent T cell receptor (TCR) signaling suppresses these specific "bystander" features. Mechanistically, t...去小宇宙查看完整单集简介
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