351-RHOA Regulates Mitochondria-ER Contact Sites

This article identifies the small GTPase RHOA as a critical controller of mitochondria-endoplasmic reticulum contact sites (MERCS). Through a genome-wide screen, scientists discovered that RHOA facilitates organelle communication by directly binding to the ER protein VAPB, which stabilizes its interaction with the mitochondrial protein PTPIP51. The study demonstrates that manipulating RHOA levels—...去小宇宙查看完整单集简介
前往小宇宙评论区与主播互动