353-IL-36γ Armored CAR T Cells Reprogram Neutrophils

The research article describes a breakthrough in solid tumor immunotherapy using IL-36γ armored CAR T cells. While traditional CAR T therapies often struggle with antigen heterogeneity and the immunosuppressive tumor microenvironment, this study demonstrates that secreting the pro-inflammatory cytokine IL-36γ allows CAR T cells to effectively eradicate tumors. The primary mechanism involves reprog...去小宇宙查看完整单集简介
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