354-Medulloblastoma Stem Cell Programs and Progression

This research explores the molecular origins and progression of medulloblastoma, a highly aggressive pediatric brain cancer. While sequencing has defined four major molecular subgroups, current treatments fail to eliminate the stem and progenitor cells that drive tumor growth and drug resistance. The authors argue for the development of faithful human models, such as 3D organoids, to better mirror...去小宇宙查看完整单集简介
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