388-cellSTAAR: Boosting Rare Variant Association Testing

The paper introduces cellSTAAR, a novel statistical framework designed to improve the discovery of rare genetic variants within noncoding regions of the human genome. By integrating single-cell epigenetic data with whole-genome sequencing, the method identifies functional associations that are often masked in traditional bulk tissue studies. The tool specifically addresses the difficulty of linkin...去小宇宙查看完整单集简介
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