401-Epigenetic Plasticity in Germinal Centre B Cells

This research identifies a unique plasticity state in germinal center B cells that is temporarily triggered by T follicular helper (TFH) cells. Under normal conditions, these B cells undergo extensive epigenetic remodeling to adapt their function, yet they remain susceptible to malignant transformation. The study demonstrates that this flexible state, while necessary for a healthy immune response,...去小宇宙查看完整单集简介
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