407-SpaceBar: Clone Tracing via Spatial Transcriptomics

The paper introduces SpaceBar, a novel biotechnology that integrates cellular clone tracing with high-resolution spatial transcriptomics. By using a library of 96 synthetic barcodes to uniquely label cells, researchers can simultaneously monitor ancestral lineages and gene activity within their physical tissue environments. The study demonstrates the tool's effectiveness in both melanoma cultures ...去小宇宙查看完整单集简介
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