431-CellRank: Directed Single-Cell Fate Mapping

Researchers introduced CellRank, a computational framework designed to map cellular development and regeneration trajectories using single-cell data. The methodology utilizes Markov chains and Schur decomposition to identify initial and terminal states while calculating the probability of a cell reaching a specific fate. In the pancreas, the tool discovered several novel regulator genes involved i...去小宇宙查看完整单集简介
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